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Anesthesiology 118, 527536

The cell lysate was additionally centrifuged at 16,000 g for 10 min at 4 C and the clear supernatant was used immediately

We have better treatments that will elicit a significant improvement

However, it is noteworthy that there is no significant correlation between serum and cerebrospinal fluid IGFs concentrations[69] and therefore, it seems that systemic IGFs are not a major source of IGFs for CNS