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In such an experimental setting, where [MNA + ]/[MNAH TOT ] is constant but the Nernstian term [MNA + ]/[MNAH] is changing, the theoretical curve of the electrode potential versus pH is given by the following function, as [MNAH] can be expressed from equation (9): where K is the protonation constant of MNAH

While the formation of 5-(3,4-dihydroxyphenyl)--valerolactone from (+)-catechin by intestinal bacteria has already been described by Das ( Eggerthelia lenta and Adlercreutzia equolifaciens species, followed by activities of Flavonifractor plautii strains ( 2 , with monomers being linked via a single interflavan bond, are more readily cleaved compared to A-type procyanidins with two interflavan bonds ( After intake of Pycnogenol , the microbial metabolites 5-(3,4-dihydroxyphenyl)--valerolactone (previously also named -(3,4-dihydroxyphenyl)--valerolactone or M1) and 5-(3- methoxy-,4-hydroxyphenyl)--valerolactone (previously also called -(3- methoxy-,4-hydroxyphenyl)--valerolactone or M2) were identified in urine samples of a volunteer as phase II conjugates (

Lycopene is a natural pigment found in tomatoes and other red fruits and vegetables, known for its ability to combat oxidative stress and inflammation

Digital images were captured using an Olympus BX41 microscope and Olympus Color View I camera or using the Hamamatsu NDP slide scanner (Hamamatsu Nanozoomer 2.0HT)

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