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However, clinical translation still faces challenges, such as administration routes, dosage optimization, and toxicity assessment, which require further investigation

This study pioneered an in vivo self-assembly strategy to develop a PKM2 allosteric converter, dually suppressing the Warburg effect and chemoresistance in renal cell carcinoma (RCC) through an enzyme-responsive self-assembly and sustained activation mechanism

Here, we examined whether and how oxidative stress induces ferroptosis in cardiomyocytes

Ghrelin Directly Regulates Bone Formation