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Allografts, harvested from genetically similar donor rats, were prepared by removing any connective tissue and endothelial lining and then cutting to match the resected tracheal length

Tirzepatide is administered as a once-weekly subcutaneous injection, starting at 2.5 mg for 4 weeks (an initiation dose), then typically increasing to 5 mg, with possible further increases to 7.5, 10, 12.5, or 15 mg based on clinical response and tolerability

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Storage in a fridge is recommended this will ensure efficacy throughout its use.