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ScienceDirect , Schizophrenia Bulletin , vol

Activation of amylin receptors influences neuronal firing patterns associated with meal termination and reduced hunger drive

The upstream mechanism by which this happens has been a subject of mechanistic investigation, with hypotheses ranging from direct nuclear localization of the copper complex to indirect signaling via copper-dependent enzyme activity (notably superoxide dismutase 1, SOD1) and downstream transcription factor modulation