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This transporter exchanges intracellular glutamate for extracellular cystine in a 1:1 ratio 21

This creates a vicious cycle wherein oxidative stress further activates CYP2E1, aggravating lipid peroxidation, hepatocyte injury, and inflammation

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

CS has been shown to induce a number of different antioxidant defenses including the expression of enzymes and transcription factors that lead to increased synthesis of GSH [14]

A low-carbohydrate diet improves glucose metabolism in lean insulinopenic akita mice along with sodium-glucose cotransporter 2 inhibitor