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PubMed , Nutrition Research (New York, N.Y.) , vol

Am J Obstet Gynecol (2020) 223:229.e18

Human research demonstrated that methylcobalamin supplementation in patients with inadequate B12 levels improved CD4/CD8 ratio and NK cell activity, and augmented CD3-CD16+ cells, suggesting an important role in cellular immunity.[14] In other research, among homologues studied, methylcobalamin was shown to have the strongest antibody production enhancement on an in vitro system.*[15]

Chinese guideline for the diagnosis and treatment of drug-induced liver injury: an update

224,225 A randomized controlled trial demonstrated that a high-dose B-complex vitamin reduced measures of oxidative stress and inflammation, and studies have shown that B vitamin supplementation is associated with reduced risk for stroke