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215 HBV encodes a viral oncoprotein, i.e., an X protein known as HBx, which may disrupt cellular processes by interacting with transcription factors, pathways, and tumor suppressors

Instead, various transcription factors more likely respond to certain threshold levels of ROS and RNS in a manner that is dependent on both concentration and duration and is likely influenced by the presence of inflammation, DNA damage, metabolic stress, and other factors

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