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Moreover, a 5-week feeding regimen was found to be more suitable than the initial 6-week regimen for the acute demyelination model, since demyelination in the corpus callosum had already peaked/completed at this time point, and detectable remyelination was observed at 6 weeks even under the continuous feeding of CPZ (Matsushima and Morell, 2001

Funding This work was supported by the National Institutes of Health [R21DE029926-01 (A

doi: 10.1186/s12950-020-00267-z 20 DingLYuanXYanJHuangYXuMYangZet al

I work closely with each patient to determine the right protocol, adjusting dosage and timing based on your functional outcomes

The step from 0.25 to 0.5 mg doubles your dose, which is the largest relative increase in the entire titration schedule