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Additionally, GHK-Cu treatment notably upregulated HO-1 expression (Figure 6G) and downregulated NF-B p65 expression (Figure 6I)

But tag selection is far from one-size-fits-all a poor choice can reduce expression levels, lower purification efficiency, or cause abnormal protein structure and loss of function

Iron overload enhances glycolysissupporting the M1 phenotype-and increases ROS production and p53 acetylation, further driving M1 polarization

Collagen peptides exert anti-aging effects through multiple interconnected pathways