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It is advised that monoclonal antibody therapy is stopped during the third trimester of pregnancy to avoid placental transfer, as the placenta is most permeable to maternal IgG antibodies during this period (67, 70)

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Patients who did not recover are mainly elder men, with a more severe gas exchange impairment at hospital admission and a more severe clinical course during hospitalization

Clin Neuropharmacol 40:2428 Lim SH, Kim HS, Kim YK, Kim T-M, Im S, Chung ME, Hong BY, Ko YJ, Kim HW, Lee JI (2010) The functional effect of epigallocatechin gallate on ischemic stroke in rats