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The HKL-2000 package (HKL Research Inc., Charlottesville, VA, USA) was used to index, integrate and scale the X-ray diffraction data (Table S2)

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Dysregulation of SQOR has been implicated in mitochondrial diseases 52 , neurodegenerative disorders 53 and ischemiareperfusion injury 48 , highlighting its broader importance in mitochondrial redox metabolism