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Chang Y, Wei W, Zhang L, Xu HM

The neurovascular unit is usually considered to represent the integrated contributions of endothelial cells, mural cells (pericytes and smooth muscle cells (SMCs)), astrocyte endfeet and other cells, along with basement membranes (BMs), to bloodbrain barrier (BBB) function

Apart from acute settings, mechanisms such as extracellular remodeling, inflammatory signal transduction, and pro-apoptotic signaling facilitating post-infarction remodeling, can be modulated through mitochondrial ROS (Yang et al., 2019)