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Regulation of S-adenosyl methionine synthesis in the mouse embryo

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Vegans can be at risk of vitamin b12 deficiency due to not being able to get it from their diet as they dont consume animal products
Based on advancements in folate metabolism research, in 1980, scientists described the 'folate trap', a phenomenon in which the enzyme methionine synthase (MTR), in the absence of its cofactor (vitamin B12), is unable to convert homocysteine into methionine