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Qinlian Hongqu Decoction inhibits the IRE1-/IKKB-/NF-B signaling pathway in the liver, thereby attenuating inflammation and insulin resistance in NAFLD rats [147]

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PIWI-Interacting RNAs (piRNAs) in infertility Mechanism: role in transposon Silencing and germline genome integrity Modification of PiRNAs and Piwi proteins Similar to siRNAs, the majority of mature piRNAs have 2-O-methylated 3 ends, while the 5 end has a phosphate group [32, 155, 165, 415,416,417,418]