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Finally, to determine if the reduction of NADPH to NADP + was due to increased consumption by GSR, we performed a kinetic assay using stably-transfected RAW 264.7 Ms with or without oxLDL loading, LPS stimulation and the addition of 2-DG and diamide

Pharmacological modulation of PPAR receptors represents a therapeutic avenue for metabolic disease intervention, though challenges remain in targeting specificity (384)