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It is stored in the liver and whatever your body doesn't use is excreted through urine, Allen says

Systemic side effects may include nausea, gastrointestinal upset, flushing, and, in rare cases, allergic reactions such as rash, hives, or anaphylaxis

For musculoskeletal healing, injectable forms have far superior systemic bioavailability and are the standard for research

For instance, SIRT7 has been identified as a key player in the pathogenesis of immune-mediated intestinal inflammation, specifically in inflammatory bowel disease (IBD)