glutathione fe3+ ncbi reductase decreased nadph oxidase NADPH/NADP⁺ equilibrium and ROS. Glucose 6-phosphate dehydrogenase is Mathematical model for glutathione dynamics – International Journal of Molecular Medicine
International Journal of Molecular Medicine The Role of Glutathione Metabolism in Chronic Illness Development and Its Potential Use as a Novel Therapeutic Target PMC Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Frontiers Ferroptosis in idiopathic pulmonary fibrosis: mechanisms, impact, and therapeutic opportunities Translating ferroptosis into oncology: challenges, opportunities and future directions Nature Reviews Clinical Oncology
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