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In studies using human fibroblast senescence models, the contents of the product were dissolved and added to the culture system at various concentrations

Metabolism 52 , 699704 (2003)

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Additionally, 1,8-diMQ and 5-amino-1MQ showed little inhibition of COMT at maximal tested concentrations of 200 M (20% inhibition) and 600 M (10% inhibition), respectively, although no clear trend of concentration-dependent inhibition was observed

A compound that restores adipocyte metabolism without suppressing appetite could theoretically produce fat-specific weight loss that preserves lean mass a highly desirable outcome