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The slices were then incubated with primary antibodies (rabbit- - phospho-histone H2A.X (Ser139) antibody, #2577, Cell Signaling Technology, Danvers, Massachusetts, USA, 1:500 in 2% goat serum in PBS

The treatment of BLM mice with severe pulmonary fibrosis (e.g., mice who were investigated from day 28 after the administration of bleomycin) still requires further investigation

The blood-to-plasma ratio was assumed to be 1, and the previously determined f u value was applied in the CL hep calculation

As time goes on the scars begin to fade and blend in to the surrounding skin at variable levels depending upon individual patient genetics

Jiang G, Li Z, Liu F, Ellsworth K, Dallas-Yang Q, Wu M, Ronan J, Esau C, Murphy C, Szalkowski D, Bergeron R, Doebber T, Zhang BB (2005) Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1