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Bile salts primarily interact with intestinal cells through the surface receptor Takeda G protein-coupled Receptor (TGR5) and the nuclear Farnesoid X Receptor (FXR) (55)

This is the first study demonstrating that the potentiation of GABAergic synapses is associated with decreased lateral mobility of synaptic GABA A Rs

Following FOXO4 displacement, the released p53 undergoes nuclear export and mitochondrial translocation, activating the intrinsic apoptosis pathway via BAX upregulation and BCL-2 downregulation, culminating in caspase-3 cleavage and apoptotic cell death

Nerve damage: In rare cases, carpal tunnel injections can cause nerve damage