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SIRT1 activation promotes numerous anti-aging effects including enhanced mitochondrial biogenesis, improved stress resistance, reduced inflammation, and activation of cellular quality control mechanisms that remove damaged proteins and organelles

Anderson GD (2002) Children versus adults: Pharmacokinetic and adverse-effect differences

With the observation of the above docking results with the drug and carriers, it may be suggested that the hydroxyl group may serve as a prerequisite to induce inhibition at the binding pockets of the iNOS oxygenase receptor