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Glutaminolysis is associated with mitochondrial pathway activation and can be therapeutically targeted in glioblastoma

Ackerman L, Acloque G, Bacchelli S, et al

However, when the balance between ROS production and the bodys antioxidant defense systems is disrupted, ROS levels rise, resulting in oxidative stress ( Figure 1 ROS are also involved in sperm motility, which is a critical determinant of male fertility