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A drawback of this assay is that the protein of interest is attached to GST, altering its native state

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Nine patients had SD following a minimum of two cycles, and nine patients received a resveratrol and bortezomib combination, achieving an ORR (MR) of 22% by a modified intention-to-treat (ITT) population, or an ORR of 8% by ITT analysis

Based on the amount of GSH in the lysate, we calculated the GSH concentration assuming an averaged HeLa cell volume of 4,000 m 3 (refs 15, 51, 52)

Mangan MSJ, Olhava EJ, Roush WR, Seidel HM, Glick GD, Latz E (2018) Targeting the NLRP3 inflammasome in inflammatory diseases