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Jan-Feb 2012 Disease Models & Mechanisms,3(1-2):57-72

In patients with pre-existing heart failure, autophagy inhibition may exacerbate proteotoxic stress rather than confer benefit, prompting cautious evaluation in cardiac clinical trials

Hyper-inflammation (with CRS or cytokine storm) due to massive outburst of ROS, is a prominent clinical feature of COVID-19 145

Detoxifies the Body: One of the significant functions of glutathione is its role as an antioxidant, which can act as a reducing agent and interact with other molecules to remove them