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Repeat these steps with your other leg

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The enzyme that is produced from a gene with this mutation is even more misshapen and even less efficient that one produced by a gene with a single mutation

kDa, Kilodalton

However, when GHB is consumed for recreational or health promotion purposes, its concentration in the body is much higher than normal, which changes the enzyme kinetics so that these pathways operate to metabolise GHB rather than producing it