The answer is thermal degradation, not biological variability
We know that macrocytosis is a very, very late stage of B12 deficiency and that severely deficient patients may not present with this sign, the administration of folic acid also masks macrocytosis by normalising the size of the blood cells
Potential risks include: Infection risk if injections are administered in non-clinical settings without appropriate sterile technique Allergic reactions to any component of the formulation Liver toxicity theoretical concern with excessive methionine or choline Drug interactions particularly if combined with other supplements or medications Unknown long-term effects due to absence of longitudinal safety data The MHRA advises caution with unlicensed injectable products, as quality, purity, and sterility cannot be guaranteed
Who needs Vitamin B12 Shot in Little Elm and Frisco, TX
Accordingly, Article 4.2.3 was added to the 2021 Code defining Substances of Abuse as those Prohibited Substances which are specifically identified as Substances of Abuse on the Prohibited List because they are frequently abused in society outside of the context of sport.
