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3) Publications were restricted to those written exclusively in English

Cells were maintained in DMEM (HCT116, SW480, U2OS), MEM- with 1 ng ml 1 fibroblast growth factor 2 (Peprotech, hMSC) or DMEM with 1% non-essential amino acid (Gibco) and 50 g ml 1 uridine (Sigma-Aldrich) supplementation (143B), with 10% dialysed foetal bovine serum (dFBS), 50 U ml 1 penicillin and streptomycin (ThermoFisher, 15070063) and 1 mM sodium pyruvate (ThermoFisher, 11360070)

Significant reduction in melanin index is seen usually after 10 weeks

High Sugar Content: Many sodas contain high amounts of sugar, which can negatively impact your overall health and potentially interfere with the absorption and utilization of creatine

Recent evidence suggests that NF-B plays a critical role in the early events controlling the molecular response to ROS [54, 55, 58, 103]