glutathione g6pd and the (GSH) cycle Glucose-6-Phosphate Dehydrogenase deficiency - G6PD

Tea, the cacao in chocolate, red wine, red onions, olives and all the blueish berries are rich sources of polyphenols

Phytomedicine 92 , 153749 (2021)

Glutathione deficiency is usually characterized by a reduction in the body's ability to detox, inability to repair DNA, increased cell mutations, increased oxidative stress, and reduced oxygen and nutrients supply to cells

228, Dec

Although not traditionally believed to be a CYP450 enzyme involved in paracetamol oxidation, it may be that possession of this allele allows CYP3A5 to use paracetamol as a substrate and hence enhance its bioactivation with resultant liver injury