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When cuprotosis occurs, it impairs mitochondrial respiration and protein lipidation, resulting in membrane permeabilization, cellular destruction, and the activation of suicidal pathways [24] (Fig

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Microalgal fatty acids have also been reported to lyse bacterial membranes, inhibit nutrient uptake, and inhibit respiration, providing a secondary mode of antibacterial action

2.2 PBPK model development The PBPK models were implemented using the Simcyp PBPK Simulator (version 23

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