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Sestrin2 plays a protective role in AD by mitigating Ang II-induced VSMC cell apoptosis through the Nrf2 pathway (161)

doi: 10.1023/a:1011083429704

As the main methyl donor in cells, SAM also mediates a variety of methylation reactions, aside from DNA methylation, including histone, RNA, and some protein amino acid residue methylation (Teperino et al., 2010)