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In addition, GLO1 may also be an important therapeutic target by inhibiting GLO1 activity and inducing MG toxicity to selectively kill cancer cells, thus providing a new strategy for the treatment of drug-resistant cancers

VNN1, a potential biomarker for pancreatic cancer-associated new-onset diabetes, aggravates paraneoplastic islet dysfunction by increasing oxidative stress

Future research should focus on developing more precise medicines for regulating ferroptosis, such as conditionally activated prodrug design and bispecific antibody-mediated targeted delivery