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These findings align with known molecular alterations induced by hyperglycemia and are consistent with reported changes in diabetic bone tissue (Wongdee and Charoenphandhu 2011), underscoring the effectiveness of this ex vivo model in elucidating comprehensive and translatable alterations associated with diabetic bone disease (Arajo et al

Intravenous (IV) or Intramuscular (IM) injection

Thus, the 2/1PHPPM was used in the following experiments

The effects of thyrotropin-suppressive therapy on bone metabolism in patients with well-differentiated thyroid carcinoma