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245 These interactions highlight the bidirectional metabolic crosstalk between CSCs and TAMs as a key factor in tumor progression and therapy resistance

[DOI] [PubMed] [Google Scholar] 107.Smeland OB, Meisingset TW, Borges K, Sonnewald U

In ccRCC tissues, the expression of FTL, FTH1, TfR1, and IRP1/2 proteins are upregulated, while the expression of FPN protein is downregulated, showing a phenotype of iron retention where iron accumulates within cancer cells