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2003 Jan;3(1):31-7

Smilkstein MJ, Knapp GL, Kulig KW, Rumack BH: Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose

Collectively, most patients (65.4%) reported an improvement in Oswestry disability index (ODI) and visual analogue scale (VAS) throughout a follow-up of 672 months and in one study, 60 30.77% of patients reported an improvement of 1 Pfirrmann grade at 12 months

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The mean count from the three regions of a quarter-section of the retina provided a measure of overall retinal changes, which was then utilized for further statistical evaluation