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Studies suggest that RA patients with coexisting depression are more prone to overweight or obesity and exhibit elevated TG levels compared to their non-depressed counterparts (301)

In an in vitro study, Shishodia et al

10.1111/jon.12751 J

Prior work has shown that inhibiting oxidative stress regulators such as TRPA1 channels and using nanodrug-based strategies to suppress glutathione and heme oxygenase 1 (HO-1) can effectively enhance chemotherapy responses 37,38