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J., Wolvetang, E

Hypoxic conditions can upregulate GPI activity, and in RA synovial tissue cells, upregulated GPI can induce RA angiogenesis by increasing the expression of HIF-1 and VEGF (213, 214)

I didn't hear any more for a few weeks, but then one weekend Burnet wrote his clonal selection theory and said, What do you think of that? I took it away and read it, and a few days later I came back and said, Well, Sir Mac, I can't really tell you what I think of the theory