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10.1038/nn1903 Nat

27 The superposition of the pulse wave by the recurrent wave in the ascending aorta is called the augmentation pressure or augmentation index (Aix

doi: 10.1038/s41467-020-18636-w 45

These in vivo investigations have not only confirmed the reduction in metastatic nodules but have also correlated these macroscopic observations with molecular changes in the primary tumor and metastatic sites, such as decreased expression of pro-metastatic proteins (e.g., MMPs, VEGF, HIF-1) and altered activity of relevant signaling pathways (e.g., NF-B, STAT3, Wnt/-catenin) in treated animals compared to controls

Newport Beach, Costa Mesa, Irvine, and Orange County patients receive a BPC-157 protocol calibrated to the specific injury, tissue type, or gut concern being addressed