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formulations in accordance with present disclosure may be administered at dosage levels sufficient to deliver a therapeutic agent dose of about 0.1 mg/kg to about 500 mg/kg body weight, from about 0.1 mg/kg to about 250 mg/kg body weight, from about 0.1 mg/kg to about 100 mg/kg body weight, from about 0.1 mg/kg to about 50 mg/kg body weight, from about 0.1 mg/kg to about 10 mg/kg body weight, and/or about 0.1 mg/kg to about 5 mg/kg body weight, from about 1 mg/kg to about 2 mg/kg body weight, from about 1mg/kg to about 10 mg/kg, from about 5mg/kg to about 15mg from about 10 mg/kg to about 20 mg/kg body weight, from about 20 mg/kg to about 30 mg/kg body weight, from about 30 mg/kg to about 40 mg/kg body weight, from about 40 mg/kg to about 50 mg/kg body weight, from about 50 mg/kg to about 60 mg/kg body weight, from about 60 mg/kg to about 70 mg therapeutic agents described herein may be any therapeutic agents described herein

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