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doi: 10.1016/j.jaip.2022.10.027 49 CrinerGJCelliBRBrightlingCEAgustiAPapiASinghDet al

The Monocle3 package 40 was applied for pseudotime analysis to examine the trends of key gene expression

This study highlights erythroid progenitors as key immunoregulatory and virus-permissive cells in COVID-19, with dexamethasone-mediated modulation of ACE2/TMPRSS2 providing a mechanistic rationale for targeted intervention