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psychological stress, excess caffeine

1 If vitamin B 12 deficiency coexists with folate deficiency, vitamin B 12 should be replaced first to prevent subacute combined degeneration of the spinal cord

Acknowledgements This work was supported by a grant from the National Natural Science Foundation of China (No

Naturally occurring antioxidant defense mechanisms might be either enzymatic (dismutase superoxide, catalase, and glutathione peroxidase) or non-enzymatic (uric acid, ascorbic acid, bilirubin, albumin, flavonoids, -tocopherol, ubiquinol and carotenoids) [2, 4, 5]