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K562 and KOPM28 cells were cultured in Iscoves Modified Dulbeccos Medium (IMDM, Sigma, I6529) with 10% FBS

Beyond a target for therapeutic intervention, monitoring GSH catabolism holds value as a cancer diagnostic

doi: 10.1016/j.chom.2012.10.014 46 ButcherLDden HartogGErnstPBCroweSE

A major drawback of bare SeNPs due to their elemental (Se 0 ) composition appears to be the poor cellular uptake, which has been overcome by conjugation to stabilising and targeting ligands on the exterior surface of the nanoparticles [35,36,37,38,39]

Intravenous Glutathione When administered intravenously, the dosage typically falls within the range of 10 to 20 mg per kg of body weight