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In prostate and bladder cancer, the Gln metabolism antagonist JHU083 inhibits TAM Gln metabolism, resulting in increased glycolysis, disruption of the tricarboxylic acid (TCA) cycle, and impairment of purine metabolism

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Dihexa molecules can provide anti-dementia benefits and improve cognitive function

In: Hermanson GT, editor

Another model supporting a protective role of syn on amyloid burden was reported by Khan and colleagues using a novel bigenic APP/syn (APP J20/Tgl2.2) mouse at 6 months old [220]