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Anatomy and Physiology of Dorsal Penile Nerve Block The penis gets its nerve supply from some specific nerves that originate from the spine, specifically sacral nerve roots (the bottom part of the spine) S2 through S4

This suggests that no other SAM sites exist in the filament beyond S2, but it is also possible that mutation of these residues could alter another putative cryptic SAM binding site indirectly

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