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As fat tissue grows and more NNMT is produced, higher amounts of hormones and pro-inflammatory signals are produced that are responsible for weight gain and other chronic diseases such as type 2 diabetes and cardiovascular disease. NNMT is responsible for converting nicotinamide (NA) into 1-methylnicotinamide (1-MNA), which takes it out of the NAD salvage pathway (see the diagram below)

Maintaining Adequate B12 Levels Ensuring adequate Vitamin B12 intake is crucial for maintaining energy levels, neurological function, and red blood cell production

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Stick to electrolyte solutions, clear broths, and bland foods for effective stomach upset management