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Citalopram, a selective serotonin reuptake inhibitor that enhances serotonergic neurotransmission by blocking serotonin reuptake at the presynapse, restored motor coordination, aggregation, and neuronal survival in mice, and aripiprazole, an antipsychotic whose efficacy mainly reflects a combined action on dopaminergic and serotonergic signaling, reduced abundance, aggregation, and toxicity of mutant ATXN3 in vivo

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The NLRP3 inflammasome has been well studied and is known to be activated by various pathogens and molecular patterns released during cell injury or in response to environmental stimuli (171)

"Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily"

alpha-lipoic acid can improve endothelial dysfunction in subjects with impaired fasting glucose