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The nitric oxide generated through this pathway promotes vasodilation, inhibits platelet aggregation, and enhances endothelial cell survival while supporting the formation of patent, functional vessels

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A positive result does not distinguish between primary and secondary causes of IMHA.30 False-positive results are seen in both dogs and cats and can be a result of concurrent diseases such as neoplasia, infections, inflammatory conditions or recent drug administration.30 False-negative results are also common and can occur in up to 50% of all dogs with IMHA.31 Thus, you should interpret this test with caution

doi: 10.3390/biomedicines8020037 Gonzales, Junior, Pirovano, Giacomo, Chow, Chun Yuen, de Souza Franca, Paula Demetrio, Carter, Lukas M., Klint, Julie K., Guru, Navjot, Lewis, Jason S., King, Glenn F

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