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Transcriptional and post-transcriptional regulation by nickel of sodN gene encoding nickel-containing superoxide dismutase from Streptomyces coelicolor Muller

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By incorporating miRNA structures into gene therapy agents, it aims to inhibit the production of the mutant Z-AAT protein and promote the production of functional A1AT (79)

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Therefore, the interaction between SIRT1 and miR-34 plays a significant role in mediating the anti-cancer effects of 0404 in liver neoplasm [122]

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TABLE 1 Summary of mechanisms leading to tamoxifen resistance The Discovery of LEM4 and the Association Between Cell Cycle Regulators and Resistance to Tamoxifen As a competitive antagonist of estradiol, tamoxifen can bind to estrogen receptors in competition with estradiol and form a stable complex, which inhibits the transcription activity of the estrogen receptor and blocks breast cancer cells in G1 phase to inhibit tumor proliferation

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