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Glutathione S-transferases (GSTs) act as a major cellular defense against 4-hydroxyalkenals and lipid hydroperoxides formed during lipid peroxidation reactions (192)

Symptoms can include itching, rash, or swelling at the injection site

There are two consecutive reactions: from ATP and pantoate to form an enzyme-bound intermediate (pantoyl adenylate), and then the intermediate is nucleophilically attacked by -alanine to produce pantothenate and AMP [183, 184]

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The preclearing step was performed by addition of 100 ml of bead slurry to the BALF samples and next incubation for 30 minutes at 48C with gentle agitation