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Of the six KEGG pathways that were coordinately deregulated, glutathione metabolism exhibited the most significantly altered gene expression and the second highest rate of metabolite abundance change (Appendix Table S1)

Gro CJ, et al

However, both approaches remain in early stages, and their benefits and risks require further validation

Reduced glutathione, known to be one of the most powerful antioxidants in the human body, works in synergy with vitamin C and selenium to neutralize free radicals and reduce oxidative stress, protecting cells from damage caused by aging and environmental exposure